WebMay 23, 2014 · Abstract. An active-site water molecule coordinated by conserved histidine and asparagine residues seems to serve as the catalytic base in all ent-copalyl diphosphate synthases (CPSs). When these residues are substituted by alanine, the mutant CPSs produce stereochemically novel ent-8-hydroxy-CPP. Given the requisite presence of … WebChristianson DW, Cox JD: Catalysis by metal-activated hydroxide in zinc and manganese metalloenzymes. Annu Rev Biochem 1999;68: 33-57. Google Scholar. Pocker Y, Stone …

Cyclization Enzymes in the Biosynthesis of …

WebDec 12, 2003 · Kim CY, Chang JS, Doyon JB, Baird Jr TA, Fierke CA, Jain A, Christianson DW (2000) J Am Chem Soc 122:12125–12134. Article CAS Google Scholar Madder RD, Kim CY, Chandra PP, Doyon JB, Baird Jr TA, Fierke CA, Christianson DW, Voet JG, Jain A (2002) J Org Chem 67:582–584 WebDescription. Cornelia de Lange syndrome is a developmental disorder that affects many parts of the body. The features of this disorder vary widely among affected individuals and range from relatively mild to severe. … ego aio zhavici hlava

Structural biology and chemistry of the terpenoid cyclases.

WebThe year 1997 marked the 25th year of x-ray crystallographic studies of the mammalian carbonic anhydrase (CA) isozymes. These remarkable enzymes catalyze the reversible … WebTHE JOURNAL OF BIOLOGICAL CHEMISTRY D 1989 by The American Society for Biochemistry and Molecular Biology, Inc.’ Vol. 264, No. 22, Issue of August 5, pp. 12849-12853,1989 Printed in U. S.A. Binding of D-Phenylalanine and D-Tyrosine to Carboxypeptidase A* (Received for publication, March 17, 1989) WebApr 1, 2008 · From Christianson DW: Science 316 :60–61 (6 April 2007). Illustration: P Huey. Reprinted with permission from AAAS. Isoprenoid coupling and cyclization reactions are catalyzed by terpenoid synthases, a.k.a. terpene synthases or isoprenoid synthases; synthases that catalyze cyclization reactions are also referred to as terpenoid cyclases. ego ad jesum